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A study has also shown that people suffering from dialysis have lower levels of glutathione in their blood, which puts the kidney cells at risk from oxidative damage

Rac1 is a member of the Rac family of guanosine triphosphate (GTP) phosphohydrolases (GTPases), which bind both guanosine diphosphate (GDP) and GTP, leading to its inactivation or activation, respectively

In-depth investigation into the tissue-specific functions of these parallel pathways in chondrocytes and their crosstalk with the main GPX4 pathway holds significant translational medical importance for developing novel OA treatment strategies (Figure 1)

To clarify the lysate, it is typically centrifuged at high speed to pellet the insoluble material